Liposarcoma Specialist Surgeon Singapore

Resection of Adipocytic Tumors and Retroperitoneal Clearance 

We manage liposarcoma across its entire spectrum—from low-grade well-differentiated lesions to aggressive pleomorphic variants. Under the clinical direction of Dr. Saminathan Suresh Nathan, our strategy centers on the distinct genetic signatures of these tumors, such as the MDM2/CDK4 amplification. We focus on the visceral challenge of delineating margins in fatty tissue, where the tumor often mimics normal anatomy, requiring a heightened level of surgical "honesty" during wide resection.

Surgical Considerations

• Histological Grading: Tailoring resection radicality to the subtype (e.g., myxoid vs. pleomorphic), as grade is the primary driver of metastatic potential.

• Multi-Visceral Resection: In retroperitoneal cases, planning for the potential sacrifice of adjacent organs to ensure the tumor pseudocapsule remains undisturbed.

• Local Recurrence Surveillance: Rigorous follow-up protocols for well-differentiated variants, which, while low-grade, can undergo dangerous "dedifferentiation" over time.