PNET Specialist Surgeon Singapore

Management of Aggressive Neuroectodermal Malignancy 

We manage PNET (Primitive Neuroectodermal Tumor)—a member of the Ewing’s family of tumors—as a relentless race against systemic progression. Under the clinical direction of Dr. Saminathan Suresh Nathan, our strategy centers on achieving absolute local control following intensive neoadjuvant protocols. By utilizing thirty years of surgical discernment, we navigate the complex anatomy where these tumors often arise, focusing on radical wide resections that ensure no microscopic disease remains to drive a recurrence. 

Surgical Considerations

• Oncological Margin Integrity: Executing radical wide resections with verified 3D planning to address the highly invasive nature of neuroectodermal cells.

• Post-Induction Re-evaluation: Utilizing high-resolution imaging to re-map resection boundaries after the tumor has responded to systemic induction, ensuring the "original" contaminated footprint is cleared.

• Functional Reconstruction: Integration of megaprostheses or biological grafts to restore structural stability after large-volume tissue loss in the pelvis or long bones.